Tina's Turkey Florentine Casserole

A take on your traditional chicken Florentine casserole that's easy to make and sure to please.

Prep Time:
20 mins
Cook Time:
55 mins
Total Time:
1 hr 15 mins
8 servings


  • 1 (16 ounce) package penne pasta

  • ½ cup butter

  • ½ medium red onion, chopped

  • 1 tablespoon minced garlic

  • 1 (8 ounce) package sliced fresh mushrooms

  • 2 (10.5 ounce) cans condensed cream of chicken soup with herbs

  • 1 cup half-and-half

  • 1 cup freshly grated Parmesan cheese

  • 2 tablespoons lemon juice

  • 2 tablespoons Italian seasoning

  • 1 teaspoon ground cayenne pepper

  • 3 cups chopped cooked turkey

  • 5 ounces fresh spinach, roughly chopped

  • 1 cup shredded mozzarella cheese


  1. Preheat the oven to 400 degrees F (200 degrees C).

  2. Bring a large pot of lightly salted water to a boil. Add penne and cook, stirring occasionally, until tender yet firm to the bite, about 12 minutes. Drain and place in a large bowl.

  3. While the pasta is cooking, melt butter in a large skillet over medium heat. Add onion and garlic and saute until translucent, about 5 minutes. Add mushrooms and cook for about 2 minutes.

  4. Mix condensed soup, half-and-half, Parmesan cheese, lemon juice, Italian seasoning, and cayenne pepper in a bowl. Add to the skillet and reduce heat to medium-low. Cook for 12 minutes, then remove from the heat.

  5. Add turkey, spinach, and sauce to the penne; stir until well combined. Transfer to a casserole dish and top with mozzarella cheese.

  6. Bake in the preheated oven until golden brown and bubbly on top, about 30 minutes.

Nutrition Facts (per serving)

584 Calories
27g Fat
52g Carbs
34g Protein
Nutrition Facts
Servings Per Recipe 8
Calories 584
% Daily Value *
Total Fat 27g 35%
Saturated Fat 15g 74%
Cholesterol 101mg 34%
Sodium 863mg 38%
Total Carbohydrate 52g 19%
Dietary Fiber 4g 16%
Total Sugars 4g
Protein 34g
Vitamin C 9mg 44%
Calcium 313mg 24%
Iron 4mg 21%
Potassium 556mg 12%

* Percent Daily Values are based on a 2,000 calorie diet. Your daily values may be higher or lower depending on your calorie needs.

** Nutrient information is not available for all ingredients. Amount is based on available nutrient data.

(-) Information is not currently available for this nutrient. If you are following a medically restrictive diet, please consult your doctor or registered dietitian before preparing this recipe for personal consumption.

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