Butternut Squash Mac and Cheese


I received this butternut squash mac and cheese recipe from a dear friend. This is a quick, great way to incorporate a fall vegetable into a comfort food favorite. Sweet, creamy, and delicious.

Prep Time:
15 mins
Cook Time:
50 mins
Total Time:
1 hrs 5 mins


  • 1 butternut squash, halved lengthwise and seeded

  • 1 (16 ounce) package rotini pasta

  • 2 tablespoons butter

  • 2 tablespoons all-purpose flour

  • ½ teaspoon dry mustard

  • 2 cups milk

  • 6 ounces shredded white Cheddar cheese

  • 6 ounces shredded Cheddar cheese

  • ¼ cup seasoned dry bread crumbs, or as needed


  1. Preheat the oven to 400 degrees F (200 degrees C).

  2. Place squash, cut-side down, on a baking sheet.

  3. Roast squash in the preheated oven until soft, 40 to 50 minutes. Remove squash flesh from skin and set aside. Reduce oven temperature to 375 degrees F (190 degrees C).

  4. Meanwhile, bring a large pot of lightly salted water to a boil. Cook rotini in boiling water until tender yet firm to the bite, about 8 minutes; drain.

  5. Melt butter in a large saucepan over medium heat. Whisk flour and mustard into melted butter until smooth, about 1 minute. Gradually whisk milk into flour mixture until thick like heavy cream, 5 to 7 minutes. Remove from heat.

  6. Stir squash, white Cheddar cheese, and Cheddar cheese into milk mixture until cheese is melted. Stir rotini into cheese mixture. Pour cheese mixture into a 9x13-inch baking dish. Top with bread crumbs.

  7. Bake in the preheated oven until topping is golden, about 10 minutes.

Nutrition Facts (per serving)

414 Calories
16g Fat
52g Carbs
18g Protein
Nutrition Facts
Servings Per Recipe 10
Calories 414
% Daily Value *
Total Fat 16g 20%
Saturated Fat 9g 47%
Cholesterol 46mg 15%
Sodium 307mg 13%
Total Carbohydrate 52g 19%
Dietary Fiber 4g 13%
Total Sugars 6g
Protein 18g
Vitamin C 22mg 108%
Calcium 368mg 28%
Iron 3mg 15%
Potassium 577mg 12%

* Percent Daily Values are based on a 2,000 calorie diet. Your daily values may be higher or lower depending on your calorie needs.

** Nutrient information is not available for all ingredients. Amount is based on available nutrient data.

(-) Information is not currently available for this nutrient. If you are following a medically restrictive diet, please consult your doctor or registered dietitian before preparing this recipe for personal consumption.

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