Granny's Cherokee Casserole


My Granny always made this easy casserole for Thanksgiving and Christmas dinner.

Prep Time:
10 mins
Cook Time:
30 mins
Total Time:
40 mins


  • 1 pound lean ground beef

  • 1 onion, finely diced

  • 1 (14.5 ounce) can diced tomatoes

  • 1 (10.5 ounce) can condensed cream of mushroom soup

  • 1 cup instant rice

  • 2 teaspoons white sugar

  • 1 tablespoon garlic powder

  • 1 teaspoon dried thyme

  • 1 teaspoon dried oregano

  • 6 slices American cheese


  1. Preheat the oven to 350 degrees F (175 degrees C).

  2. Place ground beef and onions in a large, deep skillet. Cook over medium-high heat until beef is evenly brown. Drain any excess fat.

  3. Add tomatoes, condensed soup, rice, sugar, garlic powder, thyme, and oregano. Mix well and cook over medium heat for 10 minutes. Place in a 9x13-inch casserole dish.

  4. Top with cheese slices and bake until cheese is bubbling and browning, 15 to 20 minutes.

Nutrition Facts (per serving)

241 Calories
15g Fat
13g Carbs
12g Protein
Nutrition Facts
Servings Per Recipe 11
Calories 241
% Daily Value *
Total Fat 15g 19%
Saturated Fat 7g 35%
Cholesterol 46mg 15%
Sodium 523mg 23%
Total Carbohydrate 13g 5%
Dietary Fiber 1g 3%
Total Sugars 3g
Protein 12g
Vitamin C 5mg 27%
Calcium 101mg 8%
Iron 2mg 12%
Potassium 180mg 4%

* Percent Daily Values are based on a 2,000 calorie diet. Your daily values may be higher or lower depending on your calorie needs.

** Nutrient information is not available for all ingredients. Amount is based on available nutrient data.

(-) Information is not currently available for this nutrient. If you are following a medically restrictive diet, please consult your doctor or registered dietitian before preparing this recipe for personal consumption.

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